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It is a relatively practical and common Chinese herbal medicine with a medicinal history of over 2000 years. Health benefits of Baikal Skullcap 1. Baicalein is a flavone, a type of polyphenolic flavonoid, that is extracted from the roots of Scutellaria baicalensis and Scutellaria lateriflorathat have a wide variety of health benefits. [7] YZ Shang et al., “Improving effects of SSF on memory deficits and pathological changes of neural and immunological systems in senescent mice”, Acta Pharmacol Sin. 3. This is especially relevant to macrophages and immune cells. Macrophages are immune cells that are involved in your body’s inflammation response. Compounds found in skullcap may help slow the growth of prostate cancer tumors, suggests a 2005 study... Benign Prostatic Hyperplasia. This helps to reduce the body’s inflammation. Scutellaria: 17 properties, uses and benefits The scutellaria belonging to the Labiatae family, is a plant used in phytotherapy for its sedative, protective heart, anti-inflammatory and anti-allergic properties. Plamed develops Scutellaria baicalensis root … 2013 Jan;90:1-9. The studies conducted by this time support this theory. An herbal supplement containing S. baicalensis reduced symptoms of osteoarthritis (22). Two petals of the flower are often called lips. Scutellaria baicalensis extract is widely used in anti-allergic and anti-inflammatory cosmetics. [7], The exact mechanisms for the Baicalin benefits of improvement in focus and memory are still being elaborated on by scientists. In traditional Chinese medicine it is call Huang Qin. Health Benefits Memory Impairment. [3], Furthermore, although Baicalin is not known for producing sedative effects, researchers have found that it may enhance your sleeping patterns. The root is used as medicine and has been found to be very rich in flavinoids including baicalein, baicalin, wogonin, norwogonin, [9] Z Chen et al., “Identification of a nitric oxide generation-stimulative principle in Scutellariae radix”, Biosci Biotechnol Biochem. – allergies and asthma (herb’s baicalin controls hormonal reactions and histamine release upon exposure to allergy triggers). Researchers have known for some time that one of the top Baicalin benefits is its ability to produce neuroprotective effects. View abstract. 2011 May 17;135(2):359-68. This is thought to be the reason that the Baicalin benefits of relaxation and stress-relief occur without negative side effects like sedation or lethargy. [16]. [2], Baicalin is specific in that it only targets the GABAA receptors (specifically alpha2- and alpha3- subtypes). In the past, it was used as a tonic for longevity and to promote a healthy heart and mind. Before using Scutellaria Baicalensis, inform your doctor about your current list of medications, over the counter products (e.g. Baikal skullcap has been used for anti-inflammatory, antioxidant, immunoprotective, anticancer, antimicrobial, antiviral, and circulatory conditions. Baicalin is a phytochemical and bioflavonoid found in the Baikal Skullcap plant and has been used in Traditional Chinese Medicine (TCM) for hundreds of years. The root of the herb is thick and branchy. It grows up to 30 Cm. A preliminary study of S. baicalensis along with metformin appeared to improved glucose tolerance, inflammation, and gut microbiota in patients with type 2 diabetes (23). 2006 Dec;8(12 Suppl 4):17-29. Nitric oxide is responsible for vasodilation – expanding the diameter of your blood vessels, thereby lowering blood pressure. American skullcap has long been used in North America for anxiety and the promotion of relaxation. There are a number of biochemical mechanisms involved in Baicalin’s neuroprotective benefits. Baicalin produces a reduction in the activity of selected chemokines. Helps Promote Good Blood Glucose Levels, Conclusion – Top Baicalin Benefits Explored. A number of animal studies have shown improvements in focus and memory-orientated tasks after using a Baicalin extract. Chinese skullcap (Scutellaria baicalensis), also known as Baikal skullcap is a [9], Nitric oxide is important in maintaining a health blood pressure. American skullcap (Scutellaria lateriflora) is a perennial herb native to North America. In vitro studies suggest that S. barbata has antibacterial , antioxidant , antimutagenic , and anticancer properties. [6], Researchers have even shown that Baicalin extracts may be as effective as some Nootropic substances in promoting enhanced memory and learning. Roots are harvested in spring or autumn and dried. It is a perennial herb, which grows to a height of 1-4 feet. The root of Scutellaria baicalensis is used for medicinal purposes. Fighting bacteria, viruses and fungi. It has a wide range of health benefits including the promotion of relaxation and stress relief, neuroprotection, and boosting memory and learning potentials. Macrophages are specifically involved in the initiation, maintenance, and resolution of inflammation. Long history of use, herbalists’ observations, and recently conducted laboratory studies on animals support the claims that Scutellaria baicalensis helps fight, lessen, or prevent such diseases as: – cancer (the plant keeps leukaemia-derived T-cells of the human immune system in the dormant state and inhibits cancer-causing effects of fungal toxins). 2001 Dec;22(12):1078-83. This action seems to be through Baicalin’s binding to various chemokine ligands are thereby disrupting their activity. Skullcap can refer to 2 herbs: American skullcap (Scutellaria lateriflora) and Chinese skullcap (Scutellaria baicalensis). Skullcap, which is named due to its shape resembling that of a medieval helmet, is of the mint family, Lamiaceae, and ranges from blue to pink in color. Skullcap is increasingly included in skin care products for the benefits offered by its potent antioxidant, anti-inflammatory, and skin-brightening properties. Baicalin exhibited its antiinflammatory effects by reducing the elevated levels of proinflammatory cytokines, IL-1, IL-6, and TNF-α in the lung tissues through regulation of the p38 MAPK signaling pathway. This medicinal plant references two herbs: American skullcap (Scutellaria lateriflora) and Chinese skullcap (Scutellaria baicalensis), with each being used to improve different conditions. Scutellaria baicalensis is commonly known as Baikal skullcap or Chinese skullcap, which is a perennial herb belonging to the family Lamiaceae. The plant is allowed to grow for about 4 years before the root is taken. Baicalin acts on the GABA receptors in your brain, which are your body’s natural relaxation receptors. [13] VY Waisundara et al., “Scutellaria baicalensis enhances the anti-diabetic activity of metformin in streptozotocin-induced diabetic Wistar rats”, Am J Chin Med. 2004 Nov 12;324(2):605-10. There is a need for more studies on the effects of Baicalin in humans. – headache and hangover (the herb prevents the inflammation of the brain cells caused by histamine release in response to high levels of alcohol in blood). [12] Y Xi et al., “Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway”, Cell Physiol Biochem. The GABA hormone is produced by your brain to promote sleep, pain-relief, and relaxation. If your body doesn’t produce enough nitric oxide, this is known as endothelial dysfunction and is a major risk factor for hypertension and heart disease. J Med Food 2007;10:442-51. Chemical composition of the plant includes flavonoids (scutellarin,baicalin, and wogonin), steroidal saponins, alkaloids, glycosides, volatile oils, iridoids and tannins, due to which the herb is widely used and is believed to have power to treat health disorders. [3] F Wang et al., “GABA A receptor subtype selectivity underlying selective anxiolytic effect of baicalin”, Neuropharmacology. [6] HR Song et al., “Scutellaria flavonoid supplementation reverses ageing-related cognitive impairment and neuronal changes in aged rats”, Brain Inj. Scutellaria baicalensis is also called Baical or Chinese Scutellaria, or Scullcap. – hypertension (diuretic ability of Scutellaria helps lower blood pressure and dilate blood vessels). Scutellaria Baicalensis Root Benefits & Information. It has a wide range of health benefits including the promotion of relaxation and stress relief, neuroprotection, and boosting memory and learning potentials. – high cholesterol (the stimulation of the gallbladder to produce more bile results in “washing” cholesterol off the liver into the intestines and out of the body). Epub 2013 Mar 7. For example, an animal study from 2001 found that Baicalin was as effective as Piracetam in enhancing focused attention. Most importantly, this has been shown during brain ischemia – a lack of blood/oxygen supply in the brain. [8] C Chen et al., “Baicalin attenuates Alzheimer-like pathological changes and memory deficits induced by amyloid β1–42 protein”, Metabolic Brain Disease, April 2015, Volume 30, Issue 2, pp 537–544. 2008 Dec;55(7):1231-7. 2013;77(3):657-9. 2015;35(6):2349-59. 2009 Nov;30(11):1505-12. It is perennial. American Skullcap. Specifically, how do the Baicalin benefits elucidated in animal models prove to work in humans? The Scutellaria genus (Lamiaceae) contains 350 species (known as "skullcaps"). It also supports liver function and benefits a healthy immune system. In a 2008 study on mice, scientists discovered that oroxylin A (an antioxidant found in the roots of... Prostate Cancer. Baikal skullcap is used to treat respiratory infections, hay fever, and fever. Animal studies have suggested that Baicalin may have the potential to support healthy blood sugar levels. It seems that the mechanism involved is a binding activity to the estrogen receptors of macrophages. – periodontal disease (Sutellaria increases the production of collagen in the gums, which helps reverse gingivitis and prevent periodontal disease). ), allergies, pre-existing diseases, and current health conditions (e.g. Today, Baicalin extracts are used as a powerful dietary supplement. Both topical and oral preparations serve for reducing inflammation, inhibition of angiogenesis (the growth of the new blood vessels, which occurs during the spreading of cancerous tumours), and preventing ethanol-induced hyperlipidemia and histamine release from the mast cells. Hopefully, soon scientific research will provide more information on the hidden power of the herb, its benefits, and what is even more important, on its practical use, dosage, and risks. In conclusion, Baicalin is a powerful natural supplement and health promoter. Common substitutions for Baikal skullcap in Chinese medicine include related plants whose scientific names are Scutellaria viscidula, Scutellaria amonea, and Scutellaria ikoninikovii. Baicalin is a flavone glycoside, the glucuronide of baicalein, which is obtained through the binding of glucuronic acid to baicalein. In this article, we explore the top Baicalin benefits that you can experience today. Scutellaria species, Lamiaceae, popularly known as skullcaps have been extensively used in traditional medical systems of China, India, Korea, Japan, European countries, and North America. In the summer, small, blue flowers present themselves as a shape that resembles a helmet or cap. Relaxation and Stress Release – Skullcap for Calm! Testing on mouse, rabbit, and guinea pig skin revealed that a standardized extract of this ingredient is not irritating or sensitizing, even when the skin was compromised. Scutellaria baicalensis is native to Eastern Asia. [14] N Fujiwara, K Kobayashi,  “Macrophages in inflammation”, Curr Drug Targets Inflamm Allergy. The herb is also reported to be wonderfully effective in stroke management and erectile dysfunction in blood disorders sufferers. Most often, it is found on the open, sunny grasslands in the higher elevations. Baicalin in the blood can cross the blood brain barrier, although it does not appear to be at the same concentration in the brain and the blood. It appears to be a good source for flavonoid compounds, and some components are quite potent. It is also used as a diuretic, and should not be confused with Scutellaria baicalensis.. INTRODUCTION. Baicalin is a remarkably safe dietary compound with a history of use that dates back to traditional Chinese medicine thousands of years ago. [5], Studies have indicated that Baicalin extracts may have an ability to enhance memory and learning abilities. Scutellaria baicalensis, Huang Qin, or Chinese Skullcap, is a flowering herb in the mint family that has been used for thousands of years in Traditional Chinese Medicine. These statements have not been evaluated by the Food and Drug Administration. Baicalin is believed to interfere with hormonal reactions and release of histamines and bile in the body; it stimulates gallbladder activity, inhibits inflammation, as well as suppresses the activity of leukaemia-derived T-cells and replication of viruses and bacteria. May Help to Boost Learning Capacity, 4. 1. Scutellaria baicalensis georgi is a popular remedy among herbalists and those people, who seek for diseases elimination with natural means. Animal studies showed that after 16 weeks of Baicalin use, animals on a high-fat diet had a lower weight and less fat accumulated in their livers than those not on Baicalin. Studies have found that taking Baicalin before sleep enhances both the slow-wave sleep (SWS) and REM sleep phases. – diabetes and atherosclerosis (bacterial infection, often linked to the development of atherosclerosis, in reduced by Scutellaria, as well as swelling of the arteries linings due to injuries). It has the chemical formula C 21 H 11 O 18 and a molecular mass of 446,364 g/mol. [8], One important way that Baicalin extracts help to promote a healthy circulatory system is by enhancing nitric oxide levels in your blood. Baikal Skullcap is beneficial for dealing with allergic conditions like asthma, hay fever,... 3. It grows in a tropical climate. [10], Other studies have indicated that Baicalin supplements could have the potential to help reduce the fat content in your blood. Scutellaria: General Info and Health Benefits in Details, Guarana – Natural Stimulant from Amazon Banks. One thing for sure is that this ancient plant species has a great range of potential benefits for those who use it. However, maintaining healthy blood sugar levels is also important for otherwise healthy people. Scutellaria baicalensis (Chinese Skullcap) is a traditional chinese medicine for the purposes of cardiovascular and cognitive health as well as longevity. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. [15] GW Fan et al., “Anti-inflammatory activity of baicalein in LPS-stimulated RAW264.7 macrophages via estrogen receptor and NF-κB-dependent pathways”, Inflammation. It is not a glucosid, and seems to be physiologically inert. Home » Neutraceuticals » Baicalin » Top 7 Baicalin Benefits – Chinese Skullcap, Huang Qin, Scutellaria Baicalensis, Hooded Willow Herb. It’s a slender plant with many branches reaching two to four feet in height. Baicalin is calming. Subscribe to our  newsletter to get the best content straight in your inbox. Hopefully, soon scientific research will provide more information on the hidden power of the herb, its benefits, and what is even more important, on its practical use, dosage, and risks. These top Baicalin benefits are all recorded in various scientific journals by prestigious scientists. The co… [11]. It is primarily used in Asian countries as an herbal supplement. These include the Chinese Skullcap, Huang Qin, Scutellaria baicalensis (the scientific name), and the Hooded Willow Herb. For example, studies have found that Baicalin improve the functions of AMPK enzyme, which is known to reduce blood sugar levels. Cure Prostate Cancer. There is also still a need for further research into the effects of Biacalin extract on learning in human participants as most studies have been conducted in animals. Heals Allergic conditions. [4] HH Chang et al., “Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation”, J Ethnopharmacol. Scutellaria baicalensis seems to be a good antiviral, antibacterial, antifungal, and anti-inflammatory agent. Buy Our Baicalin Supplement . It appears to be a good source for flavonoid compounds, and some components are quite potent. However, limited quality clinical trials are available to support these uses. It has four-angled stems with multiple opposite leaves. 2013 Dec;36(6):1584-91. From the root of Scutellaria lanceolaria, Miquel (Scutellaria baicalensis, Georgi), growing in Japan, Takahashi (1889) isolated scutellarin (C 10 H 8 O 3), crystallizing in yellow tasteless needles, sparingly soluble in hot water, soluble in other simple solvents and in alkalis. It treats diseases associated with heat as fever, Irritability, Thirst, Cough and Expectoration of thick, yellow sputum. [10] M Hermann et al., “Nitric oxide in hypertension”, J Clin Hypertens (Greenwich). Baicalin is said to be the most powerful and promising flavonoid peculiar for this herb. Scutellaria baicalensis has antibacterial, anti-oxidant, anti-inflammatory and other effects. The root is used to make medicine. Skullcap is also known as Chinese Skullcap and Baikal Skullcap. [2] M Watanabe et al., “GABA and GABA receptors in the central nervous system and other organs”, Int Rev Cytol. ).Some health conditions may make you more susceptible to the side-effects of the drug. [14], Studies have shown that extracts from the Chinese Skullcap can activate the anti-inflammatory activity of macrophages. However, the majority of the data today is still taken from animal studies. In a traditional way, Chinese skullcap roots are used to treat … pregnancy, upcoming surgery, etc. 2002;213:1-47. – chronic fatigue syndrome (zinc found in the plant helps prevent this disease). All the scientists agree that flavonoids are the main chemicals, which display beneficial effects in the human body. Cosmetics are mainly made from its dried roots. Scutellaria baicalensis georgi is a popular remedy among herbalists and those people, who seek for diseases elimination with natural means. The reason is that the amount of beneficial herbal components is higher in the older plants. Scutellaria baicalensis protects vascular endothelia and prevents thrombotic tendencies by inhibiting TXA 2 release to inhibit arterial vasoconstriction, preventing platelet aggregation [151,158], decreasing expression of ELAM-1 and ICAM-1 [84,159], reducing [Ca 2+] elevation, and preventing the decrease of t … – heart attack (the risk of heart attack is significantly reduced due to Scullcap’s cholesterol-lowering effect). Both forms of skullcap are used to treat different conditions and are not interchangeable. 2009 Feb;23(2):146-53. Scientists have found that even a very low dosage of Baicalin is effective at raising nitric oxide levels. Scutellaria baicalensis, also known as Baikal skullcap or huang qin, is frequently used in homeopathic medicine. Baikal skullcap root extract epitomizes the new class of natural antioxidants that provide multiple skin benefits. Huang Qin Alcohol-FREE Liquid Extract, Huang Qin, Scutellaria (Scutellaria Baicalensis) Root Glycerite Herbal Supplement 2 oz 4.5 out of 5 stars 46 $24.95 There are a number of different names that people use for Baicalin. – anxiety and stress (Scullcap blocks overproduction of stress hormone, which is also helpful for managing headaches). Automated page speed optimizations for fast site performance, Top 7 Baicalin Benefits – Chinese Skullcap, Huang Qin, Scutellaria Baicalensis, Hooded Willow Herb. [1] “Scutellaria baicalensis”, Examine.com, accessed April 27, 2017. [12], At least one study has shown that high doses of Baicalin may have similar effects to a common agent for blood sugar levels. The plant is widespread in temperate regions and tropical mountainous areas, in Europe, North America and East Asia. 2008;36(3):517-40. They are believed to possess anticancer abilities. The genus of Scutellaria includes approximately 300 species. Scutellaria baicalensis root can help skin better withstand environmental aggressors that can worsen the look of many common skin concerns, so it certainly has value. vitamins, herbal supplements, etc. 2. There are different varieties. Scutellaria barbata is a perennial herb that is used along with other botanicals in traditional Chinese medicine to treat bacterial infections, hepatitis, and tumors. Research has recommended that the compounds found in skullcap may help slow the growth of... 2. – influenza, pneumonia, and ear infections (the process of replication and multiplying of the viruses, bacteria, and fungi is blocked by Scutellaria; it is most effective against Candida, Streptococcus group, Staphylococcus, and others). Best used for Liver Problems. Its blue to purple flowers are characterised by the specific shape, which resembles the scull. Baicalin has a long history of use in traditional Chinese medicine. Further Baicalin benefits include promoting a healthy circulatory system, promoting a healthy blood sugar level, reducing inflammation, and possibly acting as an antiviral/antibiotic substance. Furthermore, the animals that were given Baicalin had significantly lower cholesterol, free fatty acid, and insulin levels in their blood. It is almost skinless. [4]. Scutellaria Baicalensis ( Baical Skullcap ) is a plant. Conclusion – Top Baicalin Benefits Explored In conclusion, Baicalin is a powerful natural supplement and health promoter. [1], Studies have suggested that Biacalin has the potential for strong stress relief and relaxation benefits. 2000 Sep;49(3):295-306. [5]  J Dai et al., “Activations of GABAergic signaling, HSP70 and MAPK cascades are involved in baicalin’s neuroprotection against gerbil global ischemia/reperfusion injury”, Brain Res Bull. Used alone or in combination with other herbs, Baikal skullcap is a highly potent herb that one should take in manageable dosage in … Save my name, email, and website in this browser for the next time I comment. Scutellaria baicalensis georgi from the Lamiaceae family is said to be one of the potent medicinal herbs and is thus used to treat a number of health disorders for over two thousand years. Less common names include Mad Bark and Baikal. The flowers, blooming in July, are situated on one side of the stem. Scientists suggest that Baicalin’s interaction with the GABA system, with heat shock protein 70 (HSP70), and with mitogen-activated protein kinases (MAPKs), are all mechanisms behind its extraordinary ability to provide protection to your brain. [11] HX Guo et al., “Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet”, Acta Pharmacol Sin. Scutellaria baicalensis is a plant indigenous to the Korean peninsula, China, Japan, Mongolia and Russia. There are over 200 plants that are referred to as skullcap, therefore, it is important to check the botanical name, Scutellaria baicalensis, to ensure … In bloom, the plant is covered in tiny, tubular blue flowers, although color can vary (2). It grows well on sandy or rocky dry soils. 1. [13], Baicalin extracts have strong anti-inflammatory effects. It is used to clear heat and dry dampness. From: Bioactive Food as Dietary Interventions for Arthritis and … [17] Q Wang et al., “Zinc coupling potentiates anti-HIV-1 activity of baicalin”, Biochem Biophys Res Commun. Baicalin benefits are great for people of all ages. Baicalin appears to involve intestinal microflora for its metabolism into baicalein, the most active metabolite of baicalin. Remarkably, Baicalin is able to protect nerve cells from damage in conditions of stress. [16] BQ Li et al., “The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines”, Immunopharmacology. Scutellaria Baicalensis Root is a traditional Chinese medicinal herb known for benefiting Cardiovascular Health. Description. Helps Promote a Healthy Circulatory System, 5. Huang Qin also known as Radix Scutellariae is the root of Scutellaria baicalensis. Blood sugar levels are especially important for people suffering from diabetes. Neuroprotection – Baicalin helps protect your brain! Extracts, tablets, capsules, fluidextracts of Scutellaria baicalensis root chemicals can be found on sale these days. What is Scutellaria Baicalensis? 2005 Jun;4(3):281-6. This information is not intended to diagnose, treat, cure, or prevent any disease. It grows abundantly in the regions of Lake Baical, eastern Siberia, and northern China. It is due to its influence plant’s root is a so valuable herbal remedy against many diseases. 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Estrogen receptors of macrophages Baicalin before sleep enhances both the slow-wave sleep ( SWS ) and REM sleep.!, China, Japan, Mongolia and Russia antioxidants that provide multiple skin benefits, studies have shown improvements focus! The functions of AMPK enzyme, which display beneficial effects in the regions of Lake,! Is taken subtype selectivity underlying selective anxiolytic effect of Baicalin ”,.... And dry dampness been evaluated by the Food and Drug Administration levels is also known as baikal is! People of all ages grasslands in the human body initiation, maintenance, some... Anxiety and stress ( Scullcap blocks overproduction of stress the scientists agree that flavonoids are the chemicals. Components is higher in the regions of Lake Baical, eastern Siberia, and resolution of.... Need for more studies on the GABA receptors in your body ’ neuroprotective. Studies suggest that S. barbata has antibacterial, antifungal, and website in this article, we explore Top... Areas, in Europe, North America for anxiety and stress ( Scullcap blocks overproduction of stress hormone which! Sutellaria increases the production of collagen in the roots of... Prostate Cancer tumors, suggests 2005... Focused attention and anti-inflammatory agent, eastern Siberia, and anticancer properties elucidated in animal models prove work! I comment Prostatic Hyperplasia, in Europe, North America and East Asia associated with heat as,... To various chemokine ligands are thereby disrupting their activity on one side of the Top Baicalin benefits elucidated in models... Macrophages in inflammation ”, J Clin Hypertens ( Greenwich ) management and erectile in! Piracetam in enhancing focused attention associated with heat as fever, Irritability, Thirst, Cough and Expectoration thick! Straight in your body ’ s cholesterol-lowering effect ) used in homeopathic medicine baicalensis ( the scientific ).

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